SolubleBioScience - Optimizing Protein Formulations
We provide services, instrumentation and consumable kits to industry that improve the solubility and stability profile of pharmaceutical formulations thus opening the gateway to the most effective treatment pathways. Our technology can save pharma up to one year in determining the optimal solution equaling a significant costs savings in the drug development cost framework.
Many proteins are not very soluble or stable, especially at the high concentrations often needed for research, therapeutics, vaccines, scientific reagents, and other applications. Keeping protein therapeutics soluble and stable, until they are ready to be used, is a difficult challenge faced by industry.These drugs often display unwanted aggregation during purification and formulation optimization which can lead to changes in protein activity and a higher immunogenicity risk potential that formulation teams must address as early as possible. SolubleBioScience provides a service that supports the pharmaceutical industry’s need for early assessments while reducing time and saving money associated with this task.
We have multiple kits available for purchase for customers needing an immediate guide for increasing solubility and stability of their protein: Order on-line and kits ship by the next day!
- OptiSol Protein Solubility Screening Kit
- OpitResc Protein Aggregate Solubilization Kit
- OptiTherm Protein Thermal Stability Kit
Our Solubility and Stability Kits Are Perfect if you need to:
- Quickly evaluate the aggregation behavior of your protein
- Screen different buffers to support protein stability at high concentrations
- Keep an antigen soluble while removing certain components from the buffer
- Find optimal conditions for stability of proteins following purification
- Quickly optimize purification conditions
Our Solubility and Stability kits can help if you are dealing with:
- Undesired Antibody or protein aggregation
- Reversible precipitation of proteins during elution off a purification column
- Insoluble protein at neutral pH
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